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Marlies Knipper Selected Research

Hidden Hearing Loss

10/2020Age-Dependent Auditory Processing Deficits after Cochlear Synaptopathy Depend on Auditory Nerve Latency and the Ability of the Brain to Recruit LTP/BDNF.
1/2020Guanylyl Cyclase A/cGMP Signaling Slows Hidden, Age- and Acoustic Trauma-Induced Hearing Loss.
1/2019Lower ototoxicity and absence of hidden hearing loss point to gentamicin C1a and apramycin as promising antibiotics for clinical use.

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Marlies Knipper Research Topics

Disease

20Hearing Loss (Hearing Impairment)
01/2021 - 03/2002
12Tinnitus
12/2021 - 06/2003
8Noise-Induced Hearing Loss (Acoustic Trauma)
10/2020 - 07/2010
8Deafness (Deaf Mutism)
01/2020 - 08/2004
6Wounds and Injuries (Trauma)
01/2020 - 04/2008
5AIDS-Related Complex (ARC)
01/2021 - 09/2008
3Hidden Hearing Loss
10/2020 - 01/2019
3Presbycusis
01/2020 - 04/2007
3Hearing Disorders (Hearing Disorder)
01/2018 - 01/2016
2Hyperacusis (Phonophobia)
01/2021 - 01/2021
2Neurodegenerative Diseases (Neurodegenerative Disease)
01/2020 - 07/2007
1Sensorineural Hearing Loss
01/2021
1Autistic Disorder (Autism)
01/2021
1Brain Diseases (Brain Disorder)
01/2021
1Ototoxicity
01/2019
1Memory Disorders (Memory Loss)
01/2018
1Optic Nerve Diseases (Optic Neuropathy)
10/2015
1Macular Degeneration (Age-Related Maculopathy)
10/2015
1Glaucoma
10/2015
1Neuralgia (Stump Neuralgia)
10/2014
1Hypersensitivity (Allergy)
10/2014
1Hypothyroidism
12/2008
1Autosomal Recessive Deafness
12/2008
1Ganglion Cysts (Ganglion)
11/2007
1Machado-Joseph Disease (Spinocerebellar Ataxia Type 3)
07/2007
1Tremor (Tremors)
07/2007
1Autosomal Recessive 31 Deafness
03/2006
1Usher Syndromes (Usher Syndrome)
12/2005
1Neoplasms (Cancer)
01/2005
1Herpes Simplex
09/2004
1Body Weight (Weight, Body)
06/2003

Drug/Important Bio-Agent (IBA)

14Proteins (Proteins, Gene)FDA Link
01/2021 - 12/2005
11Brain-Derived Neurotrophic Factor (BDNF)IBA
01/2021 - 10/2003
4SalicylatesIBA
01/2015 - 04/2008
4Messenger RNA (mRNA)IBA
01/2013 - 04/2007
3ParvalbuminsIBA
01/2021 - 01/2018
3Pharmaceutical PreparationsIBA
01/2016 - 06/2003
2Potassium Channels (Potassium Channel)IBA
01/2021 - 08/2004
2Biomarkers (Surrogate Marker)IBA
01/2021 - 01/2017
2Adrenal Cortex Hormones (Corticosteroids)IBA
01/2018 - 02/2013
2CorticosteroneIBA
01/2018 - 02/2013
2Large-Conductance Calcium-Activated Potassium Channels (Maxi-K Channels)IBA
10/2012 - 02/2009
2Sodium Salicylate (Salicylate, Sodium)IBA
09/2008 - 06/2003
1Nerve Growth Factors (Neurotrophins)IBA
01/2020
1atrial natriuretic factor receptor AIBA
01/2020
1Natriuretic PeptidesIBA
01/2020
1Glial Cell Line-Derived Neurotrophic Factor (GDNF)IBA
01/2020
1apramycinIBA
01/2019
1Gentamicins (Gentamicin)FDA LinkGeneric
01/2019
1NeomycinFDA LinkGeneric
01/2019
1Anti-Bacterial Agents (Antibiotics)IBA
01/2019
1Paromomycin (Paromomycin Sulfate)FDA LinkGeneric
01/2019
1AminoglycosidesIBA
01/2019
1gentamicin CIBA
01/2019
1Protein Isoforms (Isoforms)IBA
01/2018
1GlucocorticoidsIBA
01/2018
1Spironolactone (Aldactone)FDA LinkGeneric
01/2018
1Mifepristone (RU 486)FDA Link
01/2018
1Mineralocorticoid Receptors (Mineralocorticoid Receptor)IBA
01/2018
1SolutionsIBA
01/2016
1methanesulfonate salt 2-hydroxy-4,4'-diamidinostilbeneIBA
01/2016
1Choline O-Acetyltransferase (Choline Acetyltransferase)IBA
01/2016
1myosin VIIBA
10/2015
1Retinaldehyde (Retinal)IBA
10/2015
1rat PDCD5 proteinIBA
01/2015
1N-Methyl-D-Aspartate Receptors (NMDA Receptors)IBA
01/2015
1N-Methylaspartate (NMDA)IBA
01/2015
1EsketamineIBA
01/2015
1Microfilament Proteins (Actin Binding Proteins)IBA
08/2013
1CalciumIBA
05/2013
1AntibodiesIBA
01/2013
1Fluorescent Dyes (Fluorescent Probes)IBA
01/2013
1AMP-Activated Protein KinasesIBA
10/2012
1Cell Adhesion MoleculesIBA
06/2012
1Carcinoembryonic AntigenIBA
06/2012
1Thyroid Hormone Receptors beta (TR beta)IBA
02/2009
1GTP Phosphohydrolases (GTPases)IBA
12/2008
1ChloridesIBA
12/2008
1GABA-A Receptors (GABA(A) Receptor)IBA
09/2008
1Midazolam (Versed)FDA LinkGeneric
09/2008
1LipofuscinIBA
02/2008
1Estrogens (Estrogen)FDA Link
02/2008
1Low Density Lipoprotein Receptor-Related Protein-2IBA
02/2008
1Trefoil Factor-3IBA
01/2008
1K Cl- CotransportersIBA
10/2007
1ConnexinsIBA
10/2007
1Member 2 Solute Carrier Family 12IBA
10/2007
1Proton-Translocating ATPases (ATPase, H+)IBA
10/2007
1Ataxin-3IBA
07/2007
1polyglutamineIBA
07/2007
1Phenobarbital (Luminal)FDA Link
10/2006
1KCNQ1 Potassium ChannelIBA
10/2006
1Retinoblastoma ProteinIBA
01/2005
1Fibroblast Growth Factor 2 (Basic Fibroblast Growth Factor)IBA
09/2004
1PotassiumIBA
08/2004

Therapy/Procedure

4Therapeutics
12/2021 - 03/2002
2Cochlear Implants (Cochlear Implant)
01/2021 - 01/2020
1Injections
01/2016